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产品中心 药物靶点和Fc受体 药物靶点

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Glycoprotein/GP RBD hFc chimera protein, Ebola virus-Q7T9D9

Ebola virus EBOV (subtype Sudan,strain Gulu),GP,Envelope glycoprotein,GP (1,2)

价格 ￥4,000.00 （ 供应商现货 ： 3-5个工作日）
货号 UA030077
规格
数量
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产品介绍 评论(0)

产品规格

  • 分子别名

    Ebola virus EBOV (subtype Sudan, strain Gulu), GP, Envelope glycoprotein, GP (1,2)

  • Accession

    Q7T9D9

  • 表达序列

    Met33-Asp320 with Human IgG1 Fc Tag at the C-terminus

  • 表达宿主

    HEK293

  • 分子量

    73-95kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE & ＞90% by SEC-HPLC

  • 标记

    Unconjugated

  • 标签

    Human IgG1 Fc

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, PH7.4, 5% trehalose

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. Wang, Han et al.Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1.Cell.Volume 164;Issue 1:258 - 268

  • 稀释度

背景介绍

  • Ebola virus glycoprotein (GP1), acting as a receptor-binding subunit, is crucial for the virus entry process. In the late stages of infection, GP1 downregulates key host cell surface molecules, including integrins such as ITGA1-6, which can disrupt cell adhesion and potentially lead to compromised vascular integrity.

  • 电泳

    • 1μg (R: reducing condition).

  • 体积排阻色谱(SEC-HPLC)

    • The purity of Glycoprotein/GP RBD hFc chimera protein, Ebola virus-Q7T9D9 is more than 90% determined by SEC-HPLC.

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