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产品中心 药物靶点和Fc受体 药物靶点

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CD44/CDw44/ECMR-III His Tag Protein, Human

CD44,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1

价格 ￥2,500.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010712
规格
数量
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产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    CD44,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1

  • Accession

    P16070-1

  • 表达序列

    Gln21-Pro220, with C-8*His

  • 表达宿主

    HEK293

  • 分子量

    43-60kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4.

  • 溶解方法

    Reconstitute at 0.1-1mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.Review Front Cell Neurosci. 2015 May 7;9:175. eCollection 2015.

背景介绍

  • CD44 is a type I transmembrane protein and a member of the cartilage link protein family. Human CD44 has a 20 amino acid (aa) signal sequence, an extracellular domain (ECD) with a 100 aa hyaluronan-binding disulfide-stabilized link region and a 325-530 aa stem region, a 21 aa transmembrane domain, and a 72 aa cytoplasmic domain. CD44 is the major surface hyaluronan (HA) receptor implicated in intercellular and cell-matrix adhesion, cell migration and signaling. CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms.

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

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