APC Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)
Killer cell lectin-like receptor subfamily B member 1C,CD161 antigen-like family member C,Lymphocyte antigen 55c (Ly-55c),NKR-P1.9,NKR-P1C,Natural killer cell surface protein P1-40 (NKR-P1 40),CD161c,Ly55c,Nkrp1c,Klrb1c
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宿主来源
Rabbit抗原名称
NK1.1/CD161分子别名
Killer cell lectin-like receptor subfamily B member 1C; CD161 antigen-like family member C; Lymphocyte antigen 55c (Ly-55c); NKR-P1.9; NKR-P1C; Natural killer cell surface protein P1-40 (NKR-P1 40); CD161c; Ly55c; Nkrp1c; Klrb1c免疫原
Recombinant Protein细胞定位
MembraneAccession
P27814克隆号
S-428-32抗体类型
Recombinant mAb抗体同种型
IgG应用
FCM反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein A浓度
0.2 mg/ml标记
APC性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 5μl per million cells in 100μl volume | Ms |
NK1.1/CD161, also known as KLRB1, is a receptor protein expressed on the surface of natural killer (NK) cells and certain T cells. In mice, NK1.1 belongs to the NKRP1 receptor family and interacts with C-type lectin-related molecules, playing a role in immune recognition and regulation. In humans, CD161 on NK cells interacts with ligands such as LLT1, and this interaction is inhibitory, helping to regulate NK cell function. Additionally, CD161 is involved in intracellular signaling pathways, such as the AKT pathway, which influences NK cell activity. This protein is also a marker for different subsets of NK cells, with high expression in certain mature and cytotoxic NK cell populations.
流式分析
Flow cytometric analysis of Mouse NK1.1/CD161 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with Alexa Fluor® 488 Rat Anti-Mouse CD49b antibody (S0B8023) and either APC Rabbit IgG Isotype Control (Left panel) or SDT APC Rabbit Anti-Mouse NK1.1/CD161 Antibody (Right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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