Cytokeratin 19 fragment (CY211) Recombinant Rabbit mAb (Alexa Fluor^® 488 Conjugate) (SDT-197-28)

CYFRA 21-1

价格￥1,056.00 （供应商现货： 3-5个工作日）

货号 S0B1566

规格

10μl25μl100μl1ml

数量

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产品规格

稀释度

应用	稀释度
IF	1:200

背景介绍

Cytokeratin 19 fragment (CYFRA 21-1) is a fragment of cytokeratin 19 that is typically associated with epithelial cell cancers, including NSCLC, and is typically associated with the SQLC type. Since cytokeratins are structural proteins of keratin-containing intermediate filaments found in the epithelial cells, their degradation produces soluble fragments which are measurable in the blood of lung cancer patients as a tumor marker. Other examples of cytokeratin fragments include tissue polypeptide antigen and tissue polypeptide-specific antigen. CYFRA 21-1 is known to be correlated with disease response and the prognosis of lung cancer but cannot be used to differentiate cancer patients from patients with respiratory diseases.

免疫荧光
- IF shows positive staining in paraffin-embedded human breast cancer. Anti-Cytokeratin 19 fragment (CY211) (Alexa Fluor® 488 Conjugate) antibody was used at 1/200 dilution (Green) and incubated overnight at 4°C. Counterstained with DAPI (Blue). Heat mediated antigen retrieval with EDTA buffer pH9.0 was performed before commencing with IF staining protocol.
- IF shows positive staining in paraffin-embedded human lung adenocarcinoma. Anti-Cytokeratin 19 fragment (CY211) (Alexa Fluor® 488 Conjugate) antibody was used at 1/200 dilution (Green) and incubated overnight at 4°C. Counterstained with DAPI (Blue). Heat mediated antigen retrieval with EDTA buffer pH9.0 was performed before commencing with IF staining protocol.