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物种
SARS-CoV-2Accession
P0DTC2表达序列
RVQPTESIVRFPNITNLCPFDEVFNATRFASVYAWNRKRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKVGGNYNYRYRLFRKSNLKPFERDISTEIYQAGNKPCNGVAGVNCYFPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKGGGGSHHHHHHHHHH
表达宿主
HEK293分子量
35 kDa纯度
>95%内毒素含量
<0.1EU/μg标记
Unconjugated性状
Lyophilized Powder溶解方法
Reconstitute at less than 1 mg/mL according to the size in deionized water after rapid centrifugation.储存条件
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Sars-cov-2 (2019-NCOV) infects human respiratory epithelial cells through binding to human ACE2 receptors. Spike protein is a large type I transmembrane protein containing two subunits S1 and S2.S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing cell surface receptors. S2 contains the basic elements required for membrane fusion. S protein plays a key role in inducing neutralizing antibody and T cell responses as well as protective immunity.
生物活性
Immobilized SARS-CoV-2 (BA.4&BA.5/Omicron) RBD, His Tag at 4 μg/mL (50 μL/well) can bind Human ACE2, hFc tag (S0A0071) with EC50 of 20.33-31.67 ng/ml.
电泳
2μg（R: reducing conditions）
引用文献(1)
- A Self-Assembled Nanovaccine with BA. 4/5 Receptor-Binding Domain and CpG Oligodeoxynucleotides Induces Broad-Spectrum Neutralization against SARS-CoV-2 …
C Yang, E Li, X Guo, W Xie, Y Wang, X Huang, S Chiu
Nano. 2025 Apr 23 ; 17
影响因子： 17.1
货号：S0A2004产品名称：SARS-CoV-2 (BA.4&BA.5/Omicron) RBD, His Tag
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