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物种
Human分子别名
T-cell surface glycoprotein CD3 delta chain, T-cell receptor T3 delta chain, CD3dAccession
P04234表达序列
Protein sequence(P04234, Phe22-Ala105, with C-10*His) FKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDLGKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGGGGSHHHHHHHHHH
表达宿主
HEK293分子量
Predicted MW: 11.2 kDa Observed MW: 18-25 kDa纯度
＞90% by SDS-PAGE标记
Unconjugated性状
Lyophilized Powder缓冲体系
Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.
溶解方法
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.储存条件
12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
CD3 delta is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene.
生物活性
Immobilized CD3 epsilon Fc Chimera Protein, Human (Cat. No. UA010199) at 2 μg/mL (100 μL/well) can bind Human CD3 delta, His tag with EC50 of 3.8-4.6 μg/ ml.
电泳
2μg（R: reducing conditions）
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