顶刊加持・多肿瘤模型验证|斯达特动物/体内功能性抗体优选

顶刊加持・多肿瘤模型验证|斯达特动物/体内功能性抗体优选

多肿瘤模型功能性抗体
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顶刊加持・多肿瘤模型验证|斯达特动物/体内功能性抗体优选
一、购买功能性抗体为何选择斯达特?
斯达特抗体优势示意 media/image1.jpeg
二、已验证适用肿瘤模型(高分文献实证)
肿瘤类型 货号 品名 期刊 影响因子 文献作者 日期
该文献主要探讨肝脏乙酰辅酶A代谢通过乙酸调控神经炎症和抑郁易感性,未直接作用于特定肿瘤类型(研究对象为慢性社交挫败应激模型小鼠的神经机制) S0B0593 Invivo anti-mouse PD-L1 Recombinant mAb (D265A) Cell Metab. 30.90 Hepatic acetyl-CoA Y Cao, Y Zhao, T Deng, Q Zhou, G Hu, ZL Hu, YY Jiang 2025 Sep 23
胰腺导管腺癌(Pancreatic ductal adenocarcinoma, PDAC) S0B0594 Invivo anti-mouse PD-1 Recombinant mAb (D265A) Materials Today. 21.1 Microneedle Patch-Aided Intratumor Co-Delivery of FOLFIRINOX, Surufatinib and αPD-1 for Synergistic Efficacy of Combined Chemo-and Immuno-Therapy of PDAC T Kong, X Xu, C Wu, Z Qiu, BY Hu, Z Qi, H Dong 2025 Jul 28
乳腺癌(4T1细胞系,小鼠乳腺癌模型) S0B0594 Invivo anti-mouse PD-1 Recombinant mAb (D265A) ACS Nano. 16.1 Ascorbic Acid-Derived Supramolecular Gels Induce Immunogenic Ferroptosis in Cancer Cells to Potentiate Tumor Immunotherapy Wenjiao Cai,Yuelan Sun,Wenyue Xu, Xiuru Kuang,Zhe Zhang, Xiang Cao, Junyu Xu, Yi Li, Yongzhuo Huang,Shiyang Shen 2025 Sep 16
三阴性乳腺癌(Triple-negative breast cancer, TNBC) S0B0594 Invivo anti-mouse PD-1 Recombinant mAb (D265A) Acta Pharmaceutica Sinica B. 14.6 A lymph node-targeted cell-nanoadjuvant conjugate enhances dendritic cell-T cell crosstalk for cancer immunotherapy Shuangshuang Hu,Wenzhe,Zhiwen Zhao,Xindi Qian,Linyang Jiang,Ying Cao,Dan Yan,Lesheng Teng,Yaping Li 2025 Dec 23
非小细胞肺癌(Non-Small Cell Lung Cancer, NSCLC) S0B0594 Invivo anti-mouse PD-1 Recombinant mAb (D265A) Nature Chemical Biolog. 13.7 A small molecule targets LIC1 to suppress lung tumor growth by inducing autophagy Jia-Luo Huang, Lei-Ming Wu, Shu-Qi Wu, Fang-Yu Yuan, Han-Zhuang Weng, Dong Huang, Lu Gan, Shuo-Bin Chen, Gui-Hua Tang & Sheng Yin 2025 Oct 16
非小细胞肺癌(Non-small cell lung cancer, NSCLC) S0B0594 Invivo anti-mouse PD-1 Recombinant mAb (D265A) J Exp Clin Cancer Res. 12.8 Lactylation-driven KRT19 promotes non-small cell lung cancer progression by suppressing cellular senescence Cai Zhang, Yue Du, Yangyang Ji,Xiaoxiao Ye,Jingyao Lian,Haonan Zhou,Zihan Gao,Huiping Xu,Yuehan Tang,Yanhong Fan,Lu Zheng 2025 Dec 04
宫颈癌(Cervical Cancer, CC) S0B0594 Invivo anti-mouse PD-1 Recombinant mAb (D265A) J Immunother Cancer. 10.6 Inhibiting CMTM4 reverses the immunosuppressive function of myeloid-derived suppressor cells and augments immunotherapy response in cervical cancer J Ding, H Hu, Y Zhu, X Xu, B Yin 2025 Jun 13
前列腺癌(Prostate cancer) S0B0594 Invivo anti-mouse PD-1 Recombinant mAb (D265A) Front Immunol. 5.9 Urokinase-type plasminogen activator deficiency enhances CD8+ T cell infiltration and anti-PD-1 therapy efficacy in prostate cancer Xiaoyi Li,Xiao Zhang,Xing Fu,Hong Wu 2025 Sep 01
肺腺癌(Lung adenocarcinoma, LUAD) S0B0594 Invivo anti-mouse PD-1 Recombinant mAb (D265A) CANCER RESEARCH AND TREATMENT. 4.1 Lipid Metabolism Related Gene ACSL3 as a Biomarker for Predicting Immunotherapy Outcomes in Lung Adenocarcinoma T He, J Hu, H Guo, M Diao, Y Wang, Y Wu, L Cheng 2025 Feb 20
HPV阳性口咽鳞状细胞癌(HPV-positive Oropharyngeal Squamous Cell Carcinoma, OPSCC) S0B0594 Invivo anti-mouse PD-1 Recombinant mAb (D265A) Disease Models & Mechanisms. 3.3 Immunological dynamics in orthotopic versus subcutaneous murine models of HPV-positive oropharyngeal cancer Minzi Mao, Ke Qiu, Lan Feng, Yao Song,Yufang Rao, Shuo Li,Danni Cheng, Xiuli Shao, Chuanhuan Jiang, Shenglan You, Wei Xu,Geoffrey Liu, Jadwiga Jablonska, Stephan Lang, Shuaicheng Li, Fei Chen,Yu Zhao, Jianjun Ren 2025
上皮性卵巢癌(Epithelial ovarian cancer, EOC) S0B0594 Invivo anti-mouse PD-1 Recombinant mAb (D265A) ORIGINAL RESEARCH. 2.49 SLC40A1-mediated positive feedback loop with M1 macrophages suppresses epithelial ovarian cancer progression G Wang, S Huang, B Yin, F Shangguan, J Ma 2026 Jan 14
三、抗体验证结果(来自中科院药物所)

📚 部分引用文献(精选)
  • Microneedle Patch-Aided Intratumor Co-Delivery of FOLFIRINOX, Surufatinib and αPD-1 for Synergistic Efficacy of Combined Chemo-and Immuno-Therapy of PDAC. T Kong, X Xu, C Wu et al. Materials Today. 2025 Jul 28. 影响因子:21.1
  • Ascorbic Acid-Derived Supramolecular Gels Induce Immunogenic Ferroptosis in Cancer Cells to Potentiate Tumor Immunotherapy. Wenjiao Cai, Yuelan Sun et al. ACS Nano. 2025 Sep 16. 影响因子:16.1
  • A lymph node-targeted cell-nanoadjuvant conjugate enhances dendritic cell-T cell crosstalk for cancer immunotherapy. Shuangshuang Hu, Wenzhe et al. Acta Pharmaceutica Sinica B. 2025 Dec 23. 影响因子:14.6
  • A small molecule targets LIC1 to suppress lung tumor growth by inducing autophagy. Jia-Luo Huang, Lei-Ming Wu et al. Nature Chemical Biolog. 2025 Oct 16. 影响因子:13.7
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* 斯达特体内功能性抗体已验证数十种肿瘤模型,高分文献引用超过30篇,品质可靠,助力肿瘤免疫研究。

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