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产品规格
物种
Cynomolgus分子别名
thymic stromal lymphopoietin;Accession
A0A7N9CAT7表达序列
Tyr29-Gln159, with His tag at the C-Terminus.
表达宿主
HEK293分子量
The protein has a predicted MW of 16.3 kDa. Due to furin cleavage site, the protein migrates to 12 kDa&23-30 kDa based on Bis-Tris PAGE result.纯度
> 95% as determined by Bis-Tris PAGE & > 90% as determined by HPLC内毒素含量
<1EU/μg活性
Immobilized Cynomolgus TSLP, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human TSLPR, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA.标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
溶解方法
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.储存条件
12 months from date of receipt, -20 to -70 °C as supplied.
3 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
背景介绍
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells.
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