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产品中心 药物靶点和Fc受体 小分子药物靶点蛋白

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USP4 Flag&His Tag Protein, Human

UBP4,UNP,UNPH

价格 ￥1,200.00 （ 1-2周）
货号 UA070050
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    UBP4,UNP,UNPH

  • Accession

    Q13107

  • 表达序列

    Ala2-Asn963, with C-terminal His

  • 表达宿主

    Baculovirus-InsectCells

  • 分子量

    111kDa (Reducing)

  • 纯度

    ＞90% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    20mMTris,500mM Nacl,10%Glycerol,3mM DTT, pH8.0

  • 储存条件

    ·12 months from date of receipt, -20 to -70 °C as supplied.
    ·1 month, 2 to 8 °C under sterile conditions after reconstitution.
    ·Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Biochem Biophys Res Commun. 2006 Jan 20;339(3):731-6.
    Oncogenesis. 2017 Jun 12;6(6):e348.

背景介绍

  • Usp4 is an oncogenic protein, because its expression with a strong promoter results in the tumorigenic transformation of NIH3T3 cells injected into nude mice. Although the structure of Usp4 is that of a deubiquitinating enzyme, neither its precise function in mammalian cells nor the mechanism of Usp4-mediated tumorigenesis is known. Usp4 functions as a deubiquitinating enzyme in human HEK293T cells and its isopeptidase activity deconjugates ubiquitin specifically from a Usp4- interacting protein Ro52.

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

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