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产品中心 药物靶点和Fc受体 膜蛋白药物靶点

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Virus-Like Particle (VLP) Protein-isotype control

VLP,Virus Like Particle,eVLP,VLPs

价格 ￥790.00 （ 供应商现货 ： 3-5个工作日）
货号 UA060024
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    HIV

  • 分子别名

    VLP,Virus Like Particle,eVLP,VLPs

  • 表达宿主

    HEK293

  • 分子量

    kDa&kDa

  • 活性

    Immobilized p55 Gag-VLP at 5.0μg/mL (100μL/well) can bind Anti-HIV1 p24 antibody with EC50 of 31.57-42.51ng/mL.

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS, 5% trehalose, PH7.4

  • 储存条件

    ·6 months from date of receipt, -60 to -80 °C as supplied.
    ·about 3 days in 2 to 8 °C.
    ·Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Belghith AA, Cotter CA, Ignacio MA, Earl PL, Hills RA, Howarth MR, Yee DS, Brenchley JM, Moss B. Mpox multiprotein virus-like nanoparticle vaccine induces neutralizing and protective antibodies in mice and non-human primates. Nat Commun. 2025 May 21;16(1):4726.

背景介绍

  • Virus-like particles (VLPs) are highly structured protein particles composed of single or multiple structural proteins of the virus. Its morphological structure is similar to that of natural virus particles, does not contain virus accounting, and has strong immunogenicity and biological activity. The empty shell structure of most VLP is icosahedral or helical structure, which is composed of several specific structural proteins. At present, it is widely used in vaccine production and antigen presentation.

  • 电泳

    • 1μg (R: reducing condition).

  • ELISA

    • Immobilized p55 Gag-VLP (Cat. No. UA060024) at 5.0μg/mL (100μL/well) can bind Anti-HIV1 p24 antibody with EC50 of 0.063-0.078 ug/mL

  • DLS

    • The mean peak Radius of VLP is 120-180 nm with more than 95% intensity as determined by dynamic light scattering (DLS)

  • 电镜

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