热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 蛋白 细胞因子

所有图片（1/3）

GDF-15/MIC-1 Protein, Mouse

Growth/differentiation factor 15,GDF-15,Macrophage inhibitory cytokine 1,MIC-1

价格 ￥1,150.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040564
规格
数量
收藏 分享
产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1

  • Accession

    Q9Z0J7

  • 表达序列

    Ser189-Ala303

  • 表达宿主

    CHO

  • 分子量

    24-25 kDa (Non-Reducing)

  • 纯度

    >95% by SDS-PAGE & HPLC.

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    4mM HCl

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in Reconstitute Buffer after rapid centrifugation.

  • 储存条件

    ·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    ·3 months, -20 to -80℃ under sterile conditions after reconstitution.
    ·1 week, 2 to 8℃ under sterile conditions after reconstitution.
    ·Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. Review Front Immunol. 2020 May 19;11:951.

背景介绍

  • Growth differentiation factor 15 (GDF-15) is a polypeptide hormone belonging to the transforming growth factor β (TGF-β) superfamily. GDF-15 is highly expressed in placenta and is expressed at lower levels in kidney, pancreas, prostate and colon. Similarly to other TGF-beta family proteins, GDF-15 is synthesized as a large precursor protein that is cleaved at the dibasic cleavage site (RXXR) to release the carboxy-terminal domain. GDF-15 has been studied to have a wide range of biological functions in physiology and pathology, especially in aging, cancer, and metabolic processes.

  • 电泳

    • 2μg (R: reducing condition, N: non-reducing condition).

  • 反相高效液相色谱(RP-HPLC)

    • >95% as determined by RP-HPLC.

  • ELISA

    • Immobilized GDF-15 Protein, Mouse (Cat. No. UA040564) at 2.0μg/mL (100μL/well) can bind GFRAL Fc Chimera Protein, Human (UA011250) with EC50 of 3.0-3.5 ng/mL.

评论(0)