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产品中心 蛋白 细胞因子

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LIF Protein, Northern mallard

Leukemia inhibitory factor

价格 ￥1,800.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040539
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产品介绍

产品介绍 评论(0)

产品规格

  • 分子别名

    Leukemia inhibitory factor

  • Accession

    A0A493U243

  • 表达序列

    Arg25-Ala257 with His Tag at the C-Terminus

  • 表达宿主

    HEK293

  • 分子量

    38-48 kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE.

  • 内毒素含量

    <0.1EU/μg

  • 活性

    Test in progress.

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, 5% trehalose, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    ·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    ·3 months, -20 to -80℃ under sterile conditions after reconstitution.
    ·1 week, 2 to 8℃ under sterile conditions after reconstitution.
    ·Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Nat Biotechnol. 2025 Sep 30.

背景介绍

  • Leukemia Inhibitory Factor (LIF) is a pleiotropic cytokine belonging to the IL-6 family that plays crucial roles in maintaining pluripotency and regulating cell differentiation in avian species. In Anas platyrhynchos (Northern mallard/domestic duck), LIF has been molecularly characterized through cloning studies in related duck species.

    LIF protein represents a critical cytokine for stem cell biology, though with species-specific functional distinctions from mammalian systems. While duck ESC derivation primarily relies on ovotransferrin and small molecule inhibitors (Wnt, PKC, ALK inhibitors), LIF serves as an important synergistic factor for enhancing pluripotency and self-renewal in certain culture formulations.

  • 电泳

    • 2μg (R: reducing condition, N: non-reducing condition).

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