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IL-17A Protein, Rat

Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8 (CTLA-8)

价格 ￥1,180.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040474
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Rat

  • 分子别名

    Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8 (CTLA-8)

  • Accession

    Q61453

  • 表达序列

    Ala18-Ser150

  • 表达宿主

    HEK293

  • 分子量

    12-22kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE; >90% by HPLC;

  • 内毒素含量

    <0.1EU/μg

  • 活性

    EC50 = 9.02-10.88ng/ml

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    ·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    ·3 months, -20 to -80℃ under sterile conditions after reconstitution.
    ·1 week, 2 to 8℃ under sterile conditions after reconstitution.
    ·Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Int Immunopharmacol. 2023 Oct:123:110757.
    Front Immunol. 2020 Nov 10:11:565470.

背景介绍

  • Interleukin 17A (IL-17A) is a major member of the IL-17 cytokine family and is produced mainly by T helper 17 (Th17) cells. In healthy individuals, IL-17A has a host-protective capacity, but excessive elevation of IL-17A is associated with the development of autoimmune diseases and cancer. IL-17A is essential for modulating the interplay between commensal microbes and epithelial cells at our borders (i.e., skin and mucosae), and yet, for protecting us from microbial invaders, thus preserving mucosal and skin integrity.

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

  • 反相高效液相色谱(RP-HPLC)

    • >90% as determined by RP-HPLC.

  • ELISA

    • Immobilized IL-17A Protein, Rat (Cat. No. UA040474) at 2.0μg/mL (100μL/well) can bind Human IL-17 RA / CD217 Protein, Fc Tag with EC50 of 9.02-10.88ng/ml.

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