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物种
Human分子别名
IL13,ALRH,BHR1,MGC116786,MGC116788,MGC116789,P600,Interleukin-13Accession
P35225表达序列
Gly35-Asn146
表达宿主
E.coli分子量
Approximately 12.5 kDa, a single non-glycosylated polypeptide chain containing 112 amino acids.
纯度
＞98% by SDS-PAGE or HPLC.内毒素含量
<0.01EU/μg活性
Fully biologically active when compared to standard. The ED₅₀ as determined by a cell proliferation assay using human TF-1 cells is less than 1 ng/ml, corresponding to a specific activity of ≥ 1.0×10⁶ IU/mg.标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
20 mM PB, with 150 mM NaCl, 3% (v/v) Trehalose, pH 7.4.
溶解方法
Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.
储存条件
For long term storage, the product should be stored ≤ -20℃.
Please avoid repeated freeze-thaw cycles after reconstitution.
12 months from date of receipt, -20 to -70℃ as supplied.
1 month, 2 to 8℃ under sterile conditions after reconstitution.
3 months, -20 to -70℃ under sterile conditions after reconstitution.
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Mature human IL-13 shares approximately 58% amino acid sequence identity with mouse and rat IL-13. Despite the low homology, it exhibits cross-species activity between human, mouse, and rat. Recombinant Human IL-13 is a 12.5kDa globular protein containing 112 amino acid.
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