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产品中心 蛋白 细胞因子

ENA-78/CXCL5 Protein, Human

ENA-78 (5-78),CXCL5 (5-78),Neutrophil Activating Peptide ENA-78,Small-inducible cytokine B5

价格 ￥680.00 （ 1-2周）
货号 UA040443
规格
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    ENA-78 (5-78),CXCL5 (5-78),Neutrophil Activating Peptide ENA-78,Small-inducible cytokine B5

  • Accession

    XP_004038864

  • 表达序列

    Ala41-Asn114

  • 表达宿主

    E.coli

  • 分子量

    Approximately 8.1 kDa, a single non-glycosylated polypeptide chain containing 74 amino acids.

  • 纯度

    ＞97% by SDS-PAGE or HPLC.

  • 活性

    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration of 10.0-100.0 ng/ml.

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20 mM PB, with 100 mM NaCl, pH 7.4.

  • 溶解方法

    Before use this product, please read the direction below carefully.
    This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.
    Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
    Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.
    Further dilutions should be made in appropriate buffered solutions.

  • 储存条件

    For long term storage, the product should be stored ≤ -20℃.
    Please avoid repeated freeze-thaw cycles after reconstitution.
    12 months from date of receipt, -20 to -70℃ as supplied.
    1 month, 2 to 8℃ under sterile conditions after reconstitution.
    3 months, -20 to -70℃ under sterile conditions after reconstitution.

背景介绍

  • CXCL5 is a small cytokine also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78) . The protein is produced following stimulation of cells with the inflammatory cytokine interleukin-1 or tumor necrosis factor-alpha. In vitro, ENA-78 (8-78) and ENA-78 (9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. They are produced by proteolytic cleavage after secretion from peripheral blood monocytes. Recombinant human CXCL5 (5-78 a.a.) contains 74 amino acids and it is a single non-glycosylated polypeptide chain. Human CXCL5 shares 57% amino acid sequence identity with mouse and rat CXCL5. Recombinant Human ENA-78/CXCL5 is an 8.1kDa protein containing 74 amino acid residues.

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