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物种
Human分子别名
Cutaneous T-cell Attracting Chemokine,CCL27,ALP,Skinkine,ESkineAccession
Q9Y4X3表达序列
Phe25-Gly112
表达宿主
E.coli分子量
Approximately 10.1 kDa, a single non-glycosylated polypeptide chain containing 88 amino acids.纯度
＞96% by SDS-PAGE or HPLC.活性
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using CCR10 transfected BaF3 cells is in a concentration range of 10-100 ng/ml.标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
PBS, pH 7.0.
溶解方法
Before use this product, please read the direction below carefully.
This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.
Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.
Further dilutions should be made in appropriate buffered solutions.储存条件
For long term storage, the product should be stored ≤ -20℃.
Please avoid repeated freeze-thaw cycles after reconstitution.
12 months from date of receipt, -20 to -70℃ as supplied.
1 month, 2 to 8℃ under sterile conditions after reconstitution.
3 months, -20 to -70℃ under sterile conditions after reconstitution.
CCL27, also named IL-11 R-alpha-locus chemokine (ILC) , Skinkine, ESkine and cutaneous T-cell-attracting chemokine (CTACK) , is a small cytokine belonging to the CC chemokine family. CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin and it elicits its chemotactic effects by binding to the chemokine receptor CCR10. CCL27 can attract skin-associated memory T-lymphocytes. Studies showed it may play a role in mediating homing of lymphocytes to cutaneous sites and cell migration during embryogenesis. Mature human CCL27 is an 88 amino acid (a.a.) protein that shares 56% a.a. sequence identity with murine. Recombinant Human CTACK is a 10.2kDa protein containing 88 amino acid residues.
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