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物种
Human分子别名
CKB-8,MIP-3,MIPIF-1Accession
P55773表达序列
Arg24-Asn94表达宿主
E.coli分子量
Approximately 11.4 kDa, a single non-glycosylated polypeptide chain containing 99 amino acids.纯度
＞97% by SDS-PAGE or HPLC.活性
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-50 ng/ml.标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
20 mM PB, with 150 mM NaCl, pH 7.4.
溶解方法
Before use this product, please read the direction below carefully.
This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.
Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.
Further dilutions should be made in appropriate buffered solutions.储存条件
For long term storage, the product should be stored ≤ -20℃.
Please avoid repeated freeze-thaw cycles after reconstitution.
12 months from date of receipt, -20 to -70℃ as supplied.
1 month, 2 to 8℃ under sterile conditions after reconstitution.
3 months, -20 to -70℃ under sterile conditions after reconstitution.
MIP-3 is a CC chemokine that signals through the CCR1 receptor. Highly expressed in adult lung, liver, skeletal muscle and pancreas, this protein shows strong chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. It elicits the effects by binding to CCR1. CCL23 is reported that it can be cleaved into four forms: CCL23 (19-99) , CCL23 (22-99) , CCL23 (27-99) , CCL23 (30-99) . Recombinant Human MIP-3 is an 11.3kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
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