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物种
Human分子别名
6Ckine,Beta-chemokine Exodus-2,SLCAccession
O00585表达序列
Ser24-Pro134
表达宿主
E.coli分子量
Approximately 12.2 kDa, a single non-glycosylated polypeptide chain containing 111 amino acids.纯度
＞97% by SDS-PAGE or HPLC.活性
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration range of 10-100 ng/ml.标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
20 mM PB, with 150 mM NaCl, pH 7.4.
溶解方法
Before use this product, please read the direction below carefully.
This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.
Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.
Further dilutions should be made in appropriate buffered solutions.储存条件
For long term storage, the product should be stored ≤ -20℃.
Please avoid repeated freeze-thaw cycles after reconstitution.
12 months from date of receipt, -20 to -70℃ as supplied.
1 month, 2 to 8℃ under sterile conditions after reconstitution.
3 months, -20 to -70℃ under sterile conditions after reconstitution.
CCL21 is encoded by CCL21 gene that is located in Chr.9 and shows 21-33% identity to other CC chemokines. This chemokine contains the four conserved cysteines characteristic of β chemokines plus two additional cysteines in its unusually long carboxyl terminal domain. CCL21 is highly expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. It elicits effects by binding with CCR7, having functions of T and B lymphocytes chemotaxis and inhibiting hematopoiesis. Recombinant Human Exodus-2/CCL21 is a 12.2kDa protein containing 111 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines
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