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物种
Human分子别名
G0/G1 switch regulatory protein 19-2,LD78-beta (1-70),PAT 464.2,Small-inducible cytokine A3-like 1,Tonsillar lymphocyte LD78 beta proteinAccession
P16619表达序列
Ala24-Ala93
表达宿主
E.coli分子量
Approximately 7.8 kDa, a single non-glycosylated polypeptide chain containing 70 amino acids.
纯度
＞97% by SDS-PAGE or HPLC.活性
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10 ng/ml.标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
20 mM PB, with 150 mM NaCl, pH 7.4.
溶解方法
Before use this product, please read the direction below carefully.
This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.
Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.
Further dilutions should be made in appropriate buffered solutions.
储存条件
For long term storage, the product should be stored ≤ -20℃.
Please avoid repeated freeze-thaw cycles after reconstitution.
12 months from date of receipt, -20 to -70℃ as supplied.
1 month, 2 to 8℃ under sterile conditions after reconstitution.
3 months, -20 to -70℃ under sterile conditions after reconstitution.
CCL3L1, also named LD78-beta, is belonging to the intercrine beta (chemokine CC) family and it is encoded by the CCL3L1 gene in human. This protein binds to several chemokine receptors including chemokine binding protein 2 (CCBP2 or D6) and chemokine (C-C motif) receptor 5 (CCR5) . It is an inhibitor of HIV-1-infection and chemotactic for lymphocytes and monocytes. Recombinant human LD78β/CCL3L1 is a 7.8kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
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