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分子别名
Alanyl-tRNA Synthetase 1,AARS,PL-12表达序列
Met1-Asn968 with a C-terminal flag tag
表达宿主
E.coli分子量
Approximately 107.94 kDa, a single chain containing 979 amino acids.纯度
＞96% by SDS-PAGE or HPLC.标记
Unconjugated性状
Lyophilized Powder缓冲体系
20 mM PB, with 150 mM NaCl, 50% (v/v) Glycerol, pH 7.4.
储存条件
For long term storage, the product should be stored ≤ -20℃.
Please avoid repeated freeze-thaw cycles after reconstitution.
12 months from date of receipt, -20 to -70℃ as supplied.
1 month, 2 to 8℃ under sterile conditions after reconstitution.
3 months, -20 to -70℃ under sterile conditions after reconstitution.
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptides human AARS shares 41% identity with the E. coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific amino acids. to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. Recombinant Human AARS1 is a 107.94kDa protein globular protein containing 979 amino acid with a C-terminal flag tag.
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