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物种
Mouse分子别名
Tumor Necrosis Factor Ligand Superfamily Member 15,TNF Ligand-Related Molecule 1,Vascular Endothelial Cell Growth Inhibitor,TNFSF15,TL1,VEGIAccession
Q5UBV8表达序列
Ile76-Leu252,with a 8His, Flag tag at N-terminus
表达宿主
HEK293分子量
22-30 KDa, reducing conditions纯度
>95% by SDS-PAGE内毒素含量
<1EU/μg标记
Unconjugated标签
Flag Tag, His Tag性状
Liquid缓冲体系
PBS, pH7.4.
储存条件
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial cells. TNFSF15 is also able to regulate the expression of several important genes involved in angiogenesis. These findings are consistent with the view that TNFSF15 functions as an autocrine cytokine to inhibit angiogenesis and stabilize the vasculature.
电泳
ELISA
Immobilized Recombinant Mouse TL1A (N-8His-Flag)at 1μg/ml (100 μl/well) can bind Human TL1A Antibody (9H5)( NC092). The ED50 of Human TL1A Antibody (9H5)is 2.94 ng/ml.
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