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BD-3 Protein, Mouse

Beta-defensin 3,BD-3,mBD-3,Defensin,beta 3

价格 ￥680.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040393
规格
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    Beta-defensin 3; BD-3; mBD-3; Defensin, beta 3;

  • Accession

    Q9WTL0

  • 表达序列

    Lys23-Lys63

  • 表达宿主

    E.coli

  • 分子量

    5-8 kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE; >90% by HPLC.

  • 内毒素含量

    <0.1EU/μg

  • 活性

    EC50 = 0.020-0.052μg/ml.

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    50mM Tris, 300mM NaCl, pH8.0

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    ·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    ·3 months, -20 to -80℃ under sterile conditions after reconstitution.
    ·1 week, 2 to 8℃ under sterile conditions after reconstitution.
    ·Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Anticancer Res. 2016 Nov;36(11):5999-6004.

背景介绍

  • β-defensin-3 (mBD-3) is a member of the defensin family of antimicrobial peptides, which play crucial roles in the innate immune system. These peptides are characterized by their ability to directly kill or inhibit the growth of a wide range of pathogens, including bacteria, fungi, and viruses.
    In mice, the ortholog of human β-defensin-3 is known as mBD-14. It has been identified and characterized for its antimicrobial properties and immune-modulatory functions.
    Similar to its human counterpart, mBD-14 exhibits potent antimicrobial activity against various pathogens and can induce chemotaxis in immune cells, such as macrophages and dendritic cells. This antimicrobial peptide is expressed in various tissues, including the gastrointestinal tract and skin, where it contributes to the maintenance of mucosal and cutaneous barriers.

  • 电泳

    • 2μg (R: reducing condition, N: non-reducing condition).

  • 反相高效液相色谱(RP-HPLC)

    • >90% as determined by RP-HPLC.

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