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Epiregulin Protein, Human

Epiregulin,ER,EREG,proepiregulin

价格 ￥880.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040357
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Epiregulin; ER; EREG; proepiregulin;

  • Accession

    O14944

  • 表达序列

    Val63-Leu108

  • 表达宿主

    E.coli

  • 分子量

    6 kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE.

  • 内毒素含量

    <0.1EU/μg

  • 活性

    EC50 < 2.0ng/ml

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM Tris, 50mM NaCl, pH8.0

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    ·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    ·3 months, -20 to -80℃ under sterile conditions after reconstitution.
    ·1 week, 2 to 8℃ under sterile conditions after reconstitution.
    ·Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Gene. 2006 Jan 17;366(1):2-16. Epub 2005 Dec 27.

背景介绍

  • Epiregulin is a member of the epidermal growth factor (EGF) family of proteins that plays a key role in cell proliferation, differentiation, and tissue repair. In humans, epiregulin is a small, secreted protein that acts as a ligand for the epidermal growth factor receptor (EGFR) and ErbB4 receptor tyrosine kinases. Upon binding to its receptors, epiregulin activates downstream signaling pathways, such as the MAPK and PI3K/Akt pathways, leading to cellular responses such as cell growth, survival, and migration. Epiregulin is expressed in various tissues and is involved in processes such as wound healing, tissue regeneration, and cancer progression. Dysregulation of epiregulin signaling has been implicated in various diseases, including cancer.

  • 电泳

    • 2μg (R: reducing condition, N: non-reducing condition).

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