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BD-2 Protein, Mouse

Beta-defensin 2,BD-2,mBD-2,Defensin,beta 2

价格 ￥800.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040327
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    Beta-defensin 2; BD-2; mBD-2; Defensin, beta 2;

  • Accession

    P82020

  • 表达序列

    Ala21-Lys71

  • 表达宿主

    E.coli

  • 分子量

    5 kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE.

  • 内毒素含量

    <0.1EU/μg

  • 活性

    EC50 = 0.8-1.0 ng/ml

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.

    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.

    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Science. 2002 Nov 1;298(5595):1025-9.

背景介绍

  • Beta-defensin 2 is a key component of the innate immune system, known for its antimicrobial properties and immunomodulatory functions. It is produced by various epithelial cells in response to microbial infections and plays a crucial role in host defense against pathogens. Beta-defensin 2 exhibits potent antimicrobial activity against a wide range of microorganisms, including bacteria, fungi, and viruses, by disrupting their cell membranes. In addition to its direct antimicrobial effects, beta-defensin 2 also functions as a chemoattractant for immune cells, such as neutrophils, monocytes, and dendritic cells, promoting their recruitment to sites of infection. Furthermore, beta-defensin 2 can modulate inflammatory responses by regulating cytokine production and promoting wound healing.

  • 电泳

    • 2μg (R: reducing condition, N: non-reducing condition).

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