热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 蛋白 细胞因子

所有图片（1/2）

CCL17/TARC Protein, Human

C-C motif chemokine 17,CC chemokine TARC,Small-inducible cytokine A17,Thymus and activation-regulated chemokine

价格 ￥580.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040321
规格
数量
收藏 分享
产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    C-C motif chemokine 17; CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine;

  • Accession

    Q92583

  • 表达序列

    Ala24-Ser94

  • 表达宿主

    E.coli

  • 分子量

    10 kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE and HPLC.

  • 内毒素含量

    <0.1EU/μg

  • 活性

    Determined by its ability to chemoattract Jurkat T cells using a concentration range of 1-10.0 ng/ml.

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM PB, 500mM NaCl, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.

    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.

    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Int Immunol. 1999 Jan;11(1):81-8.

背景介绍

  • CCL17, also known as thymus and activation-regulated chemokine (TARC), is a small cytokine belonging to the CC chemokine family. It is produced by various cell types, including dendritic cells, macrophages, and endothelial cells, and plays a crucial role in regulating immune cell migration and activation. CCL17/TARC is involved in the recruitment of T cells, particularly T helper type 2 (Th2) cells, to sites of inflammation and is implicated in the pathogenesis of allergic and inflammatory diseases, such as atopic dermatitis and asthma. CCL17/TARC binds to its receptor CCR4 and mediates chemotaxis of CCR4-expressing cells, contributing to the orchestration of immune responses.

  • 电泳

    • 2μg (R: reducing condition, N: non-reducing condition).

  • 反相高效液相色谱(RP-HPLC)

    • >95% as determined by RP-HPLC.

评论(0)