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物种
Human分子别名
C-C motif chemokine 14,Chemokine CC-1/CC-3 (HCC-1/HCC-3),HCC-1(1-74),NCC-2,Small-inducible cytokine A14,Accession
Q16627表达序列
Gly28-Asn93表达宿主
E.coli分子量
7.8 kDa (Reducing)
纯度
>95% by SDS-PAGE and HPLC.内毒素含量
<0.1EU/μg活性
Test in progress.标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
20mM PB, 500mM NaCl, pH7.0溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
BMC Genomics. 2008 May 15:9:222.
CCL14a, also known as HCC-1 (Hematopoietic Cell-Derived CC Chemokine 1), is a chemokine belonging to the CC chemokine family. It is involved in immune regulation and inflammation. CCL14a/HCC-1 is produced by various cell types, including monocytes, macrophages, and dendritic cells, in response to inflammatory stimuli.
CCL14a/HCC-1 functions by binding to specific chemokine receptors on target cells, such as CCR1 and CCR5, to induce chemotaxis and activation of immune cells. It plays a role in recruiting leukocytes to sites of inflammation and modulating immune responses.
Research has shown that CCL14a/HCC-1 is implicated in various physiological and pathological processes, including immune cell trafficking, inflammatory diseases, and cancer. Understanding the role of CCL14a/HCC-1 in these processes may provide insights into potential therapeutic strategies for targeting this chemokine in the treatment of related conditions.
电泳
2μg (R: reducing condition, N: non-reducing condition).
反相高效液相色谱(RP-HPLC)
>95% as determined by RP-HPLC.
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