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CCL7/MCP-3 Protein, Human

C-C motif chemokine 7,Monocyte chemoattractant protein 3,Monocyte chemotactic protein 3 (MCP-3),NC28,Small-inducible cytokine A7

价格 ￥960.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040282
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    C-C motif chemokine 7,Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3 (MCP-3),NC28,Small-inducible cytokine A7

  • Accession

    Q7Z7Q8

  • 表达序列

    Gln34-Leu109

  • 表达宿主

    E.coli

  • 分子量

    13 kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 活性

    Test in process.

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM Tris, 300mM NaCl, pH8.0

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    J Leukoc Biol. 1996 Jan;59(1):67-74.

背景介绍

  • CCL7, also known as monocyte chemotactic protein 3 (MCP-3), is a small cytokine belonging to the CC chemokine family. It plays a crucial role in immune responses by attracting monocytes, T cells, and other immune cells to sites of inflammation or injury. CCL7 is produced by various cell types, including monocytes, macrophages, and fibroblasts, in response to inflammatory stimuli such as cytokines or microbial products.
    The protein structure of CCL7 consists of a signal peptide at the N-terminus, followed by a conserved N-terminal region and a flexible loop region. This loop region is important for receptor binding and activation of downstream signaling pathways. CCL7 exerts its biological effects by binding to specific G protein-coupled receptors, such as CCR1 and CCR2, on target cells.
    Overall, CCL7 plays a critical role in regulating the recruitment and activation of immune cells during inflammation and immune responses. Understanding the protein background of CCL7 is essential for elucidating its functions and developing therapeutic strategies targeting this chemokine pathway.

  • 电泳

    • 2μg (R: reducing condition, N: non-reducing condition).

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