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Fas Ligand/TNFSF6 Protein, Human

apoptosis (APO-1) antigen ligand 1,Apoptosis antigen ligand,APT1LG1CD95L,APTL,CD178 antigen,CD178,CD95L,CD95-L,Fas antigen ligand,Fas ligand (TNF superfamily,member 6),Fas Ligand,FASLCD95 ligand,FASLG,TNFSF6

价格 ￥1,350.00 （ 1-2周）
货号 UA040275
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    apoptosis (APO-1) antigen ligand 1,Apoptosis antigen ligand,APT1LG1CD95L,APTL,CD178 antigen,CD178,CD95L,CD95-L,Fas antigen ligand,Fas ligand (TNF superfamily,member 6),Fas Ligand,FASLCD95 ligand,FASLG,TNFSF6

  • Accession

    P48023

  • 表达宿主

    HEK293

  • 分子量

    17.7 KDa

  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Liquid

  • 缓冲体系

    PBS, pH7.4.

  • 储存条件

    • Store at ≤-70°C, stable for 6 months after receipt.
    • Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
    • Please minimize freeze-thaw cycles.


背景介绍

  • Fas ligand is also known as FasL, CD178, CD95L, or TNFSF6, is a homotrimeric type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its ability to induce apoptosis in target cells plays an important role in the development, homeostasis, and function of the immune system. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

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