SDF-1α/CXCL12 Protein, Human
CXCL12,Stromal cell-derived factor 1,SDF-1,hSDF-1,C-X-C motif chemokine 12,Intercrine reduced in hepatomas,IRH,hIRH,Pre-B cell growth-stimulating factor,PBSF,SDF1,SDF1A,SDF1B,Intercrine reduced in hepatomas (IRH,hIRH),Pre-B cell growth-stimulating factor (PBSF)
货号： UA040269
- 价格： ￥1,180
- 规格：
- 数量：
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物种
Human分子别名
Stromal cell-derived factor 1, SDF-1, hSDF-1, C-X-C motif chemokine 12, Intercrine reduced in hepatomas (IRH; hIRH), Pre-B cell growth-stimulating factor (PBSF)Accession
P48061表达序列
Lys22-Lys89表达宿主
E.coli分子量
10 kDa (Reducing)
纯度
＞95% by SDS-PAGE & HPLC内毒素含量
<0.1EU/μg活性
Testing in progress.标记
Unconjugated标签
No Tag性状
Lyophilized powder缓冲体系
20mM Tris, 800mM NaCl, PH8.0溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
Cells. 2020 Oct 13;9(10):2277.
Pharmacol Ther. 2022 Mar:231:107989.
Fractalkine (FKN, CX3CL1) is produced in neurons and is a unique chemokine that is initially translated as a transmembrane protein but can be proteolytically processed to generate a soluble chemokine. CX3CL1 signals through its unique receptor, CX3CR1, that is expressed in microglia. Within the CNS, fractalkine acts as a regulator of microglia activation in response to brain injury or inflammation. CX3CL1 has been shown to signal through its sole receptor CX3CR1, which is located on microglial cells within the central nervous system (CNS). Although both the membrane bound and soluble forms of CX3CL1 appear to interact with CX3CR1, they do seem to have different signaling capabilities.
电泳
2μg (R: reducing condition, N: non-reducing condition).
反相高效液相色谱(RP-HPLC)
>95% as determined by RP-HPLC.
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