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物种
Rat分子别名
Fibroblast Growth Factor 2,FGF-2,Basic Fibroblast Growth Factor,bFGF,Heparin-Binding Growth Factor 2,HBGF-2,FGF2,FGFBAccession
P13109表达序列
Pro10-Ser154表达宿主
E.coli纯度
>95% by SDS-PAGE
内毒素含量
<1EU/μg标记
Unconjugated性状
Lyophilized Powder缓冲体系
20mM PB, 150mM NaCl, pH 7.4.溶解方法
- Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
- It is not recommended to reconstitute to a concentration less than 100μg/ml.
- Dissolve the lyophilized protein in distilled water.
- Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存条件
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
- Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
- Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4.
生物活性
Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells.The EC50 for this effect is 0.3-1.8 ng/ml.
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