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产品中心 细胞因子 生长因子

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TIMP-2 Protein, Human

CSC-21K,TIMP2

价格 ￥1,180.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040240
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    CSC-21K,TIMP2

  • Accession

    P16035

  • 表达序列

    Cys27-Pro220, with C-terminal His Tag

  • 表达宿主

    HEK293

  • 分子量

    22-24 kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE and HPLC.

  • 内毒素含量

    <0.1EU/μg

  • 活性

    Test in progress.

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, 5% trehalose, PH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1、Sci Rep . 2021 Jan 13;11(1):1071.

背景介绍

  • TIMP metallopeptidase inhibitor 2 is also known as TIMP2, which belongs to the protease inhibitor I35 (TIMP) family. The total length of TIMP-2 Protein, Human (HEK293, His) is 194 a.a., with molecular weight of 22-24 kDa. TIMP-2 protein is a tissue inhibitor of metalloproteinases that can bind and inactivate various metalloproteinases, including collagenases, such as MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9 , MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. TIMP2 is a 22 kDa non N-glycosylated protein expressed by a variety of cell types, and plays a unique role among TIMP family members owing to its functions to regulate cellular responses to growth factors.

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

  • 反相高效液相色谱(RP-HPLC)

    • 99.451%

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