热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 蛋白 细胞因子

所有图片（1/1）

GDF-5/BMP-14 Protein, Mouse

Growth/differentiation factor 5,GDF-5,Bone morphogenetic protein 14 (BMP-14)

价格 ￥680.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040221
规格
数量
收藏 分享
产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    Growth/differentiation factor 5; GDF-5; Bone morphogenetic protein 14 (BMP-14);

  • Accession

    P43027

  • 表达序列

    Ala376-Arg495

  • 表达宿主

    E.coli

  • 分子量

    15 kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE.

  • 内毒素含量

    <0.1EU/μg

  • 活性

    EC50 < 2.0μg/ml

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    50mM HAc, pH2.9

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Nature. 1994 Apr 14;368(6472):639-43.

背景介绍

  • Growth differentiation factor 5 (GDF-5), also known as bone morphogenetic protein 14 (BMP-14), is a member of the transforming growth factor beta (TGF-β) superfamily. It plays a crucial role in skeletal development and joint formation, as well as in the regulation of cell growth and differentiation. In mice, GDF-5/BMP-14 is essential for the proper development of bones, cartilage, and joints, and mutations in the GDF-5 gene have been associated with skeletal abnormalities and joint disorders. GDF-5/BMP-14 exerts its biological activities by binding to specific cell surface receptors and activating downstream signaling pathways that regulate gene expression and cellular functions involved in skeletal development and maintenance.

  • 电泳

    • 2μg (R: reducing condition, N: non-reducing condition).

评论(0)