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物种
Human分子别名
BMP14,CDMP1,LAP-4,LPS-associated protein 4Accession
P43026表达序列
Ala382-Arg501表达宿主
E.coli分子量
28kDa (Non-reducing)
纯度
＞95% by SDS-PAGE内毒素含量
<0.1EU/μg活性
＜0.2μg/mL标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
50mM HAc, pH2.9
溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用
Jin L, Li X. Growth differentiation factor 5 regulation in bone regeneration. Curr Pharm Des. 2013;19(19):3364-73.
Human growth differentiation factor 5 (GDF5) is one of the bone morphogenetic proteins (BMPs) belonging to the transforming growth factor β (TGF-β) superfamily. It has commercial value as a therapeutic protein because of its ability to induce cartilage and bone formation, and angiogenesis in adult animals. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations of GDF5 are associated with several human and animal diseases that are characterized by skeletal deformity such as short digits and short limbs.
电泳
1μg (R: reducing condition, N: non-reducing condition).
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