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产品中心 细胞因子 白细胞介素

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IL-8/CXCL8 Protein, Canine

Interleukin-8,IL8,CXCL8,NAP-1,NAF

价格 ￥1,580.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040196
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Canine

  • 分子别名

    Interleukin-8,IL8,CXCL8,NAP-1,NAF,

  • Accession

    P41324

  • 表达序列

    Ala23-Pro101

  • 表达宿主

    E.coli

  • 分子量

    10kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE&RP-HPLC

  • 内毒素含量

    <0.1EU/μg

  • 活性

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS,PH7.4.

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. Van Damme J, Rampart M, Conings R, et al. 1990. Eur J Immunol. 20:2113-8.1/2.

背景介绍

  • IL-8(Interleukin-8) is one of the first discovered chemokines and belongs to the CXCL family, in which the first two conserved cysteines are separated by one residue. In vivo, IL-8 exists in two forms: a 77-amino acid protein produced by endothelial cells, and the more active 72- amino acid protein produced by monocytes. IL-8 is often associated with inflammation, it has been cited as a proinflammatory mediator in gingivitis and psoriasis. The functions of IL-8 are to induce rapid changes in cell morphology, activate integrins, and release the granule contents of neutrophils. Thus, IL-8 can enhance the antimicrobial actions of defense cells. It is secreted by monocytes, macrophages and endothelial cells. IL-8 signals through CXCR1 and CXCR2 to chemoattract neutrophils, basophils, and T cells. IL-8 is also a potent promoter of angiogenesis.

  • 电泳

    • 2μg (R: reducing condition, N: non-reducing condition).

  • 反相高效液相色谱(RP-HPLC)

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