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物种
Human分子别名
PPBP,B-TG1,Beta-TG,CTAP-III,CTAP3,CTAPIII,CXCL-7,LA-PF4,LDGF,MDGF,NAP2,PBP,SCYB7,TC1,TC2,TGB,TGB1,THBGB,THBGB1,pro-platelet basic proteinAccession
P02775表达序列
Ala59-Asp128表达宿主
E.coli分子量
9kDa (Reducing)纯度
＞95% by SDS-PAGE
内毒素含量
<0.1EU/μg标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
20mM Tris, 300mM NaCl, pH8.0溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
Wang YH, Shen CY, Lin SC, Kuo WH, Kuo YT, Hsu YL, Wang WC, Lin KT, Wang LH. Monocytes secrete CXCL7 to promote breast cancer progression. Cell Death Dis. 2021 Nov 17;12(12):1090. doi: 10.1038/s41419-021-04231-4 . PMID: 34789744; PMCID: PMC8599470 .
Neutrophil Activating Peptide 2 (NAP-2), also known as CXCL7, is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. Recently, it has been shown that CXCL7 is secreted by tumor infiltrating monocytes, to stimulate cancer cell migration, invasion, and metastasis, contributing to the promotion of breast cancer progression. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.
电泳
2μg (R: reducing condition, N: non-reducing condition).
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