产品介绍 引用文献(1) 评论(0)
物种
Mouse分子别名
Urogastrone, URG, Epidermal Growth FactorAccession
P01132表达序列
Asn977-Arg1029表达宿主
E.coli分子量
6.2kDa纯度
>95% by SDS-PAGE内毒素含量
<0.1EU/μg标记
Unconjugated标签
No Tag性状
Lyophilized powder缓冲体系
PBS, pH7.4溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
1.Cell Biol Int. 1995 May;19(5):413-30.
Epidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. EGF binds to epidermal growth factor receptor and stimulates an intracellular signal transduction cascade, leading to activation of genes that regulate cell proliferation, angiogenesis, motility, and metastasis. EGF mRNA and protein are expressed in a number of adult tissues, especially in epithelial cells in the gastrointestinal tract. Predominant sites of synthesis of this peptide are the submandibular glands, the Brunner glands in the small intestine and the kidney.
生物活性JSON
Measured in a cell proliferation assay using Balb/c 3T3 mouse fibroblast cells. The EC50 for this effect is less than 0.5ng/ml.
电泳JSON
2μg ( R: reducing condition, N: non-reducing condition).
引用文献(1)
- Paroxetine ameliorates corticosterone-induced myelin damage by promoting the proliferation and differentiation of oligodendrocyte precursor cells
Jingjing Bu; Yuan Liu; Yufang Zhao; Li Liu; Ji-Duo Shen; et al
Neuroscience. 2025 Mar 01 ; 0306-4522
影响因子: 2.9
货号:UA040126产品名称:EGF Protein, Mouse
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