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物种
Mouse分子别名
FGF-8c,rMuFGF-8c,AIGF,HBGF-8Accession
P37237表达序列
Gln23-Arg268表达宿主
E.coli分子量
28-29kDa纯度
>95% by SDS-PAGE内毒素含量
<1EU/μg标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
20mM Tris, 100mM NaCl, pH8.0溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.储存条件
12 months from date of receipt, -20 to -70 °C as supplied;
6 months, -20 to -70 °C under sterile conditions after reconstitution;
1 week, 2 to 8 °C under sterile conditions after reconstitution;
Please avoid repeated freeze-thaw cycles.
Fibroblast Growth Factor 8 was originally identified as an androgen-dependent growth of mouse mammary carcinoma cells. The primary transcript of mouse FGF-8 is alternatively spliced to generate at least 8 secreted isoforms that differ at their amino terminus. The differences between the isoforms exist in the number of potential N-linked glycosylation sites. In mouse, the eight isoforms are labeled as 8a through 8h. Human FGF-8 is limited to only four isoforms. Only isoforms 8a, 8b, 8e, and 8f are synthesized in humans. Mouse and human 8a and 8b isoforms are 100% identical, while the 8e and 8f isoforms are 98% identical. The FGF-8 isoforms differentially activate the various alternatively spliced forms of the FGF receptors 1-3, and FGF receptor 4. The isoform FGF-8c activates FGF R3c and FGF R4.
电泳
- 1μg (R: reducing condition, N: non-reducing condition).
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