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FGF-8e Protein, Human

FGF-8e,AIGF,HBGF 8e,KAL6

价格 ￥600.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040049
规格
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    FGF-8e,AIGF,HBGF 8e,KAL6

  • Accession

    P55075-1

  • 表达序列

    Gln23-Arg233

  • 表达宿主

    E.coli

  • 分子量

    26kDa

  • 纯度

    ＞95% by SDS-PAGE and HPLC

  • 内毒素含量

    <0.1EU/μg

  • 活性

    < 100 ng/ml

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM PB, 150mM NaCl, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.

    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.

    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1、Valve E M. et al. (2001) Increased expression of FGF-8 isoforms and FGF receptors in human premalignant prostatic intraepithelial neoplasia lesions and prostate cancer. Lab Invest. 81(6): 815-826.

背景介绍

  • Fibroblast growth factor 8e (FGF-8e), a secreted heparin-binding protein, is a member of the fibroblast growth factor (FGF) family and is an isoform of FGF-8. Alternative splicing of fgf-8 gene gives rise to potentially four (a, b, e, f) different protein isoforms in human. FGF-8 is widely expressed during embryogenesis, and mediates epithelial-mesenchymal transitions. It plays an organizing and inducing role during gastrulation, and regulates patterning of the midbrain/hindbrain, eye, ear, limb and heart in the embryo.

  • 生物活性

    • Measured in a cell proliferation assay using Balb/3T3 mouse fibroblast cells, the EC50 for this effect is 120-177 ng/ml.

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

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