KGF/FGF-7 Protein, Human

浏览次数：12

货号： UA040040

大包装询价

产品介绍引用文献(0) 评论(0)

产品规格

物种

Human
抗原名称

KGF/FGF-7
分子别名

FGF-7, Fibroblast growth factor 7, HBGF-7, Keratinocyte growth factor, KGF
Accession

P21781
表达序列

Cys32-Thr194
表达宿主

E.coli
分子量

17kDa (Reducing)
纯度

>95% by SDS-PAGE & RP-HPLC
内毒素含量

<1EU/μg
标记

Unconjugated
标签

No Tag
性状

Lyophilized powder
缓冲体系

20mM Tris, 500mM NaCl, pH8.0
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

背景介绍

Fibroblast growth factor (FGF-7), a member of FGF family, is initially found to be secreted from mesenchymal cells to repair epithelial tissues. As a well-characterized paracrine growth factor for tissue growth and regeneration, fibroblast growth factor 7 (FGF-7) is involved in a number of physiological and pathological processes, including lung disease and cancer. The stromal-derived FGFs, such as FGF-7 and FGF-10, control epithelial cell resident FGFR2IIIb activities, promote net tissue homeostasis, and restraint tumor cells from progression to malignancy.

生物活性
- Measured in a cell proliferation assay using 4MBr‑5 rhesus monkey epithelial cells，The EC50 for this effect is less than 3ng/ml.
- Measured in a cell proliferation assay using 4MBr‑5 rhesus monkey epithelial cells，The EC50 for this effect is less than 3ng/ml.
电泳(SDS-PAGE)
- 2μg (R: reducing conditions, N: non-reducing conditions).
反相高效液相色谱(RP-HPLC)
SPR
- Anti-His antibody Immobilized on CM5 Chip captured FGF-R2 (IIIb) His Tag, Human (Cat. No. UA010145), can bind KGF/FGF-7(Cat. No. UA040040), Human with an affinity constant of 0.19μM as determined in SPR assay.