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FGF-10 Protein, Human

价格 ￥950.00 （ 供应商现货 ： 3-5个工作日）
货号 UA040037
规格
数量
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产品介绍 评论(0)

产品规格

  • 物种

    Human

  • Accession

    O15520

  • 表达序列

    Leu40-Ser208

  • 表达宿主

    E.coli

  • 分子量

    19kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE & RP-HPLC

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM Tris, 150mM NaCl, pH8.0

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.

    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.

    · Please avoid repeated freeze-thaw cycles.

背景介绍

  • Fibroblast growth factor 10 (FGF-10), a secreted heparin-binding protein, is a member of the fibroblast growth factor (FGF) family and is also known as Keratinocyte Growth Factor-2 (KGF-2). FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies revealed that genetic variants of FGF10 were associated with extreme myopia in adults.

  • 生物活性

    • Measured in a cell proliferation assay using 4MBr‑5 rhesus monkey epithelial cells，The EC50 for this effect is less than 200ng/ml.

  • 电泳

    • 2μg (R: reducing conditions, N: non-reducing conditions).

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