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产品规格
物种
HumanAccession
P01563表达序列
Cys24-Glu188表达宿主
E.coli分子量
19kDa (Reducing)纯度
＞95% by SDS-PAGE
内毒素含量
<1EU/μg活性
<0.5ng/ml标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
50mM Tris, 50mM NaCl, pH8.0溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
背景介绍
IFN-α is a cytokine that has an immunomodulatory function. It plays an important role not only in antiviral activity but also in several physiologic functions, such as activation of dendritic cells and accelerated expression of major histocompatibility complex I and II molecules that may cause increased antigen presentation. Variants of human leukocyte interferon α 2 (IFN-α 2a, α 2b, and α 2c) differ from each other by changes in their coding regions at nucleotide positions 137 and 170. IFN-α 2b is an important cytokine and used for antiviral and anticancer treatment.
生物活性
- Measured by cytotoxicity assay using TF-1cells, the EC50 for this effect is less than 0.5ng/ml.
电泳
- 1μg (R: reducing conditions, N: non-reducing conditions).
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