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物种
Human分子别名
Growth hormone,GH1,Somatotropin,Growth hormone,GH,GH-N,Growth hormone 1Accession
P01241表达序列
Phe27-Phe217表达宿主
E.coli分子量
20-23kDa (Reducing)纯度
＞95% by SDS-PAGE内毒素含量
<0.2EU/μg标记
Unconjugated标签
No Tag性状
Lyophilized Powder缓冲体系
20mM Tris, 500mM NaCl, pH8.0溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Growth hormone (GH), also known as somatotropin, is a member of a family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. It is a peptide hormone that stimulates growth, cell reproduction and regeneration in humans and other animals. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland. The pulsatile release of GH into circulation is regulated by the concerted actions of the hypothalamic hormones-GH-releasing hormone (GHRH) and somatostatin (SST) as well as by signals from the periphery-ghrelin and leptin. The human GH cDNA encodes a 217 amino acid (aa.) residue precursor protein with a 26 aa. putative signal peptide. By alternative splicing, at least four isoforms of GH have been identified.
生物活性
- The EC50 as determined by a cell proliferation assay using murine Nb2-11 cells is less than 0.2ng/ml.
电泳
- 2μg（R: reducing conditions).
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