大包装询价 产品介绍 评论(0)
物种
Human分子别名
Tau-F, Tau-4, 2N4R, Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau (PHF-tau), MAPT, MAPTL, MTBT1, TAUAccession
P10636-8表达序列
Met1-Try441, with C-His tag
表达宿主
CHO分子量
Predicted MW: 47.5 kDa Observed MW: 75-90 kDa
纯度
＞90% by SDS-PAGE内毒素含量
<0.1EU/μg活性
Measured by its binding ability in a functional ELISA. Immobilized Tau-441/2N4R His Tag Protein, Human at 2 μg/mL (100 μL/well) can bind Tau Recombinant Rabbit mAb (SDT-171-67) (Cat. No. S0B0036) with EC50 of 7.3-10.1 ng/mL.标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
0.2M PBS, pH7.4.
溶解方法
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
储存条件
12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
The tau proteins (abbreviated from tubulin associated unit) form a group of six highly soluble protein isoforms produced by alternative splicing from the gene MAPT (microtubule-associated protein tau). They have roles primarily in maintaining the stability of microtubules in axons and are abundant in the neurons of the central nervous system (CNS), where the cerebral cortex has the highest abundance. They are less common elsewhere but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. Pathologies and dementias of the nervous system such as Alzheimer's disease and Parkinson's disease are associated with tau proteins that have become hyperphosphorylated insoluble aggregates called neurofibrillary tangles.
电泳JSON
2 μg（R: reducing conditions）
ELISA
Immobilized Tau-441/2N4R His Tag Protein, Human at 2 μg/mL (100 μL/well) can bind Tau Recombinant Rabbit mAb (SDT-171-67) (Cat. No. S0B0036) with EC50 of 7.3-10.1 ng/mL.
评论(0)