Glycoprotein/GP RBD hFc chimera protein, Ebola virus-ACI28624
Ebola virus EBOV (subtype Bundibugyo,strain Uganda 2007),Ebolavirus (subtype Bundibugyo,strain Uganda 2007) Envelope Glycoprotein 1 (GP1) Protein,GP,Envelope glycoprotein,GP (1,2)
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分子别名
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007), Ebolavirus (subtype Bundibugyo, strain Uganda 2007) Envelope Glycoprotein 1 (GP1) Protein, GP, Envelope glycoprotein, GP (1,2)Accession
ACI28624表达序列
Ile33 -Val308 with Human IgG1 Fc Tag at the C-terminus表达宿主
HEK293分子量
70-90kDa (Reducing)纯度
＞95% by SDS-PAGE & ＞90% by SEC-HPLC标记
Unconjugated标签
Human IgG1 Fc性状
Lyophilized Powder缓冲体系
PBS, PH7.4, 5% trehalose溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
1. Wang, Han et al.Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1.Cell.Volume 164;Issue 1:258 - 268
Ebola virus glycoprotein (GP1), acting as a receptor-binding subunit, is crucial for the virus entry process. In the late stages of infection, GP1 downregulates key host cell surface molecules, including integrins such as ITGA1-6, which can disrupt cell adhesion and potentially lead to compromised vascular integrity.
电泳
2μg (R: reducing condition).
体积排阻色谱(SEC-HPLC)
The purity of Glycoprotein/GP RBD hFc chimera protein, Ebola virus-ACI28624 is more than 93% determined by SEC-HPLC.
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