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VZVgE His Tag Protein

Envelope glycoprotein E,gE

价格 ￥1,120.00 （ 供应商现货 ： 3-5个工作日）
货号 UA030069
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 分子别名

    Envelope glycoprotein E; gE

  • Accession

    Q9J3M8

  • 表达序列

    Ser31-Tyr538
    SVLRYDDFHIDEDKLDTNSVYEPYYHSDHAESSWVNRGESSRKAYDHNSPYIWPRNDYDGFLENAHEHHGVYNQGRGIDSGERLMQPTQMSAQEDLGDDTGIHVIPTLNGDDRHKIVNVDQRQYGDVFKGDLNPKPQGQRLIEVSVEENHPFTLRAPIQRIYGVRYTETWSFLPSLTCTGDAAPAIQHICLKHTTCFQDVVVDVDCAENTKEDQLAEISYRFQGKKEADQPWIVVNTSTLFDELELDPPEIEPGVLKVLRTEKQYLGVYIWNMRGSDGTSTYATFLVTWKGDEKTRNPTPAVTPQPRGAEFHMWNYHSHVFSVGDTFSLAMHLQYKIHEAPFDLLLEWLYVPIDPTCQPMRLYSTCLYHPNAPQCLSHMNSGCTFTSPHLAQRVASTVYQNCEHADNYTAYCLGISHMEPSFGLILHDGGTTLKFVDTPESLSGLYVFVVYFNGHVEAVAYTVVSTVDHFVNAIEERGFPPTAGQPPATTKPKEITPVNPGTSPLLRYGGGSHHHHHHHH

  • 表达宿主

    HEK293

  • 分子量

    58-82kDa(Reducing)

  • 纯度

    ＞95% by SDS-PAGE & RP-HPLC

  • 活性

    Immobilized VZVgE His Tag Protein (Cat. No. UA030069) at 2.0μg/mL (100μL/well) can bind Varicella-zoster virus (VZV) / HHV-3 gE / glycoprotein E Antibody, Mouse MAb with EC50 of 1.98-3.23 ng/ mL.

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, PH7.4, 5% trehalose

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.

    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.

    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Julie K. Olson, Richard A. Santos, Charles Grose, Varicella-Zoster Virus Glycoprotein gE: Endocytosis and Trafficking of the Fc Receptor, The Journal of Infectious Diseases, Volume 178, Issue Supplement_1, November 1998, Pages S2–S6.

背景介绍

  • Varicella-zoster virus (VZV) is the prototype member of the alphaherpesvirus subgroup now designated as the Varicellovirus genus. The genome of VZV encodes at least six glyco-proteins: gB, gC, gE, gH, gI, and gL. Of the VZV glycoproteins, gE (previously designated gpI or gp98) is the most abundant virion envelope protein and the predominant VZV glycoprotein expressed on the surface of infected cells. VZV gE is a typical type I transmembrane glycoprotein, which is highly modified by N-linked and O-linked glycosylation, sialylation, and sulfation. In addition, VZV gE contains a serine/threonine casein kinase II phosphorylation site. VZV gE can also form homodimers, which are modified by tyrosine phosphorylation. During viral infection, VZV gE forms a protein complex with VZV gI. Most interestingly, VZV gE on the surface of infected cells has previously been shown to function as an Fc receptor for nonimmune IgG. Homology studies have demonstrated that gE displays a combination of structural features commonly observed in several nonviral cell surface receptors, including the Fc receptor (FcγRII) and the low-density lipoprotein (LDL) receptor.

  • 电泳

  • 反相高效液相色谱(RP-HPLC)

    • The purity of VZVgE His Tag Protein was greater than 95% as determined by RP-HPLC.

  • ELISA

    • Immobilized VZVgE His Tag Protein (Cat. No. UA030069) at 2.0μg/mL (100μL/well) can bind Varicella-zoster virus (VZV) / HHV-3 gE / glycoprotein E Antibody, Mouse MAb with EC50 of 1.98-3.23 ng/ mL.

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