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物种
Mouse抗原名称
LCN2/NGAL分子别名
NGAL, LCN2, Lipocalin-2, 24p3, MSFIAccession
P11672表达序列
Gln21-Asn200, with C-terminal 8*His
表达宿主
HEK293分子量
25-28kDa
纯度
＞95% by SDS-PAGE内毒素含量
<0.1EU/μg标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
PBS, pH7.4
溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用
1. Biomed Pharmacother. 2021 Oct; 142:112002. Epub 2021 Aug 27.
Lipocalin-2 (LCN-2) is a novel, 198 amino acid adipocytokine also referred to as neutrophil gelatinase-associated lipocalin (NGAL).It was initially found in activated neutrophils, however, many other cells, like kidney tubular cells, may produce NGAL in response to various insults.NGAL, first known as an antibacterial factor of natural immunity, and an acute-phase protein. acting as an intracellular iron carrier and protecting MMP9 from proteolytic degradation, NGAL has a clear pro-tumoral effect, as has already been observed in different tumors (e.g. breast, stomach, esophagus, brain) in humans. Recent studies have revealed that NGAL plays an important role in the physiopathology of chronic myeloid leukaemia (CML) mediated by BCR-ABL.
电泳
1μg (R: reducing condition, N: non-reducing condition).
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