FGF-R1/CD331 His Tag Protein, Human
bFGF-R-1 Protein,BFGFR Protein,CD331 Protein,CEK Protein,FGFBR Protein,FGFR-1 Protein,FLG Protein,FLT-2 Protein,FLT2 Protein,HBGFR Protein,HH2 Protein,HRTFDS Protein,KAL2 Protein,N-SAM Protein,OGD Protein
分享产品介绍 评论(0)
物种
Human分子别名
bFGF-R-1 Protein, BFGFR Protein, CD331 Protein, CEK Protein, FGFBR Protein, FGFR-1 Protein, FLG Protein, FLT-2 Protein, FLT2 Protein, HBGFR Protein, HH2 Protein, HRTFDS Protein, KAL2 Protein, N-SAM Protein, OGD ProteinAccession
P11362-7表达序列
Arg22-Ile376, with C-terminal His
表达宿主
HEK293分子量
60 -70 kDa(Reducing)
纯度
＞95%, by SDS-PAGE under reducing conditions内毒素含量
<0.1EU/μg标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
PBS, pH7.4, 5% trehalose
溶解方法
Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
FGF-R1, fibroblast growth factor receptor 1, also known as CD331, is a receptor tyrosine kinase whose ligand is a specific member of the fibroblast growth factor family. FGF-R1 is a full-length representative protein, which consists of an extracellular domain, three immunoglobulin-like domains, a hydrophobic transmembrane fragment and a cytoplasmic tyrosine kinase domain. The extracellular domain of FGF-R1 interacts with specific extracellular fibroblast growth factors, initiating a series of downstream signals and affecting cell mitosis and differentiation. FGF-R1 protein is considered to play an important role in the development of nervous system. The protein may also help regulate the growth of long bones, such as large bones in the arms and legs.
生物活性
Immobilized FGF-basic(154aa), Human (Cat. No. UA040007) at 2.5μg/mL (100μL/well) can bind Human FGF-R1/CD331, His Tag (Cat. No. UA020008) with EC50 of 0.049-0.066μg/ml.
电泳
- FGF-R1/CD331 His Tag, Human ,1.5 μg on SDS-PAGE under Non-reducing and reducing condition. The purity is greater than 95%.
反相高效液相色谱(RP-HPLC)
SPR
Anti-His antibody Immobilized on CM5 Chip captured FGF-R1/CD331 His Tag Protein, Human (Cat. No. UA020008), can bind FGF-1/FGF-Acidic Protein, Human (Cat. No. UA040032) with an affinity constant of 55.09nM as determined in SPR assay.
评论(0)