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产品中心 药物靶点和Fc受体 Fc受体类蛋白

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FCAR/CD89 His Tag Protein, Human

Immunoglobulin Alpha Fc Receptor,IgA Fc Receptor,CD89,FCAR

价格 ￥2,800.00 （ 供应商现货 ： 3-5个工作日）
货号 UA020007
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Immunoglobulin Alpha Fc Receptor; IgA Fc Receptor; CD89; FCAR

  • Accession

    P24071-1

  • 表达序列

    Gln22-Asn227, with C-terminal His

  • 表达宿主

    HEK293

  • 分子量

    42-55 kDa(Reducing)

  • 纯度

    ＞95%, by SDS-PAGE under reducing conditions

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.
背景介绍

  • FCAR, also known as Fc alpha RI or CD89, is a 50-100 kDa glycosylated bone marrow-specific type I transmembrane (TM) Fc receptor, which is a member of the immunoglobulin gene superfamily. FCAR exists on the surface of myeloid cells such as neutrophils, monocytes, macrophages and eosinophils, and mediates the immune response to pathogens. It interacts with IgA-regulated targets and triggers a variety of immune defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity and stimulating the release of inflammatory mediators. This product is made by recombinant expression of human FCAR from HEK293 cell line, purified, sterilized, filtered, packaged and freeze-dried.

  • 电泳

    • FCAR/CD89 His Tag, Human，1μg on SDS-PAGE under reducing and Non-reducing condition. The purity is greater than 95%.

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