分享产品介绍 评论(0)
物种
Human分子别名
ErythropoietinAccession
P01588表达序列
Protein sequence (P01588, Ala28-Arg193, with N-hFc tag) APPRLICDSRVLERYLLEAKEAENITTGCAEHCSLNENITVPDTKVNFYAWKRMEVGQQAVEVWQGLALLSEAVLRGQALLVNSSQPWEPLQLHVDKAVSGLRSLTTLLRALGAQKEAISPPDAASAAPLRTITADTFRKLFRVYSNFLRGKLKLYTGEACRTGDR
表达宿主
HEK293分子量
Predicted MW: 45.3 kDa Observed MW: 60-70 kDa纯度
＞95% by SDS-PAGE内毒素含量
<1EU/μg标记
Unconjugated标签
Human Fc Tag性状
Lyophilized Powder缓冲体系
Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.
溶解方法
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.储存条件
12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
Erythropoietin (EPO) is a glycoprotein hormone primarily produced by the kidneys in response to hypoxia. It stimulates red blood cell production (erythropoiesis) in the bone marrow by binding to the EPO receptor on progenitor cells. Clinically, recombinant human EPO (rhEPO) treats anemia associated with chronic kidney disease and chemotherapy. Beyond hematopoiesis, EPO exhibits tissue-protective effects in the brain and heart.
生物活性
Immobilized Human EPO Protein, hFc Tag at 2 μg/mL (100 μL/well) can bind Recombinant Human Erythropoietin R/EPO-R Protein, C-hFc&His with EC50 of 9-10 ng/ml.
电泳
2μg（R: reducing conditions）
评论(0)