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产品中心 药物靶点和Fc受体 药物靶点

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CD81 His Tag Protein, Human

26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1,Tetraspanin-28 (Tspan-28)

价格 ￥1,580.00 （ 1-2周）
货号 UA019003
规格
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1, Tetraspanin-28 (Tspan-28)

  • Accession

    P60033

  • 表达序列

    Protein sequence(P60033, Phe113-Lys201, with C-10*His)
    FVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGSSTLTALTTSVLKNNLCPSGSNIISNLFKEDCHQKIDDLFSGKGGGGSHHHHHHHHHH

  • 表达宿主

    HEK293

  • 分子量

    Theoretical: 11.4kDa Actual:11kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    12 months from date of receipt, -20 ℃ to -70℃ as supplied.

    1 month, 2 to 8℃ under sterile conditions after reconstitution.

    Please avoid repeated freeze-thaw cycles.

背景介绍

  • CD81 is a member of the transmembrane 4 superfamily and it is a cell surface glycoprotein that is known to complex with integrins. CD81 appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. Moreover, CD81 plays a critical role in Hepatitis C attachment and cell entry by interacting with virus' E1/E2 glycoproteins heterodimer. The large extracellular loop of CD81 binds the hepatitis E2 glycoprotein dimer. It also appears to play a role in liver invasion by Plasmodium species.

  • 生物活性

    • Immobilized Human CD81, His Tag at 4 μg/mL (50 μL/well) can bind CD81 Recombinant Rabbit mAb (SDT-144-22) (S0B0053) with EC50 of 4.568-6.102 ng/ml.

  • 电泳

    • 2μg (R: reducing conditions)

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